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This emerging framework has important implications for developmental tissue remodeling, the progression of organ injury, and ferroptosis-based cancer therapy
10.1038/jcbfm.2011.43 222 Nieto-BonaM
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Furthermore, reduced expression of melatonin receptor 1A (MT1) in astrocytes leads to increased pathological Ca 2+ influx, exacerbating oxidative stress and suppressing the NRF2/SLC7A11/GPX4 antioxidant axis, ultimately promoting neuronal ferroptosis (Zhang S
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